首页 > 用药指导 > 文章详情

Ambisome(安必素)安必松有何副作用

发布时间:2024-03-04 13:46:53 阅读:1493 来源:问药网
分享至

分享到微信朋友圈

×

打开微信,点击底部的“发现”,

使用“扫一扫”即可将网页分享至朋友圈。

安必素

安必素 生产厂家:迈兰(Mylan)制药有限公司 功能主治:一线抗真菌药物,治疗深部真菌感染有效率高 用法用量:用法用量  静脉用药:开始静脉滴注时先试以1~5mg或按体重一次0.02~0.1mg/kg给药,以后根据患者耐受情况每日或隔日增加5mg,当增至一次 0.6~0.7mg/kg时即可暂停增加剂量,此为一般治疗量。  成人最高一日剂量不超过1mg/kg,每日或隔1~2日给药1次,累积总量 1.5~3.0g,疗程1~3个月,也可长至6个月,视病情及疾病种类而定。  对敏感真菌感染宜采用较小剂量,即成人一次20~30mg,疗程仍宜长。  鞘内给药:首次0.05~0.1mg,以后渐增至每次0.5mg,最大量一次不超过1mg,每周给药2~3次,总量15mg左右。  鞘内给药时宜与小剂量地塞米松或琥珀酸氢化可的松同时给与,并需用脑脊液反复稀释药液,边稀释边缓慢注入以减少不良反应。  局部用药:气溶吸入时成人每次5~10mg,用灭菌注射用水溶解成0.2%~0.3%溶液应用;超声雾化吸入时本品浓度为0.01%~0.02%,每日吸入2~3次,每次吸入5~10ml;持续膀胱冲洗时每日以两性霉素B 5mg加入1000ml灭菌注射用水中,按每小时注入40ml速度进行冲洗,共用5~10日。  静脉滴注或鞘内给药时,均先以灭菌注射用水10ml配制本品50mg,或5ml配制25mg,然后用5%葡萄糖注射液稀释(不可用氯化钠注射液,因可产生沉淀),滴注液的药物浓度不超过10mg/100ml,避光缓慢静滴,每次滴注时间需6小时以上,稀释用葡萄糖注射液的pH值应在4.2以上。  鞘内注射时可取5mg/ml浓度的药液1ml,加5%葡萄糖注射液19ml稀释,使最终浓度成250μg/ml。  注射时取所需药液量以脑脊液5~30ml反复稀释,并缓慢注入。  鞘内注射液的药物浓度不可高于25mg/100ml,pH值应在4.2以上。
查看详情

Ambisome(安必素)安必松有何副作用,Ambisome(AmBisome)常见副作用包括发热、寒战、呼吸困难、恶心、呕吐、肾功能损害、低钾血症、头痛和胃肠不适。在治疗期间需要监测肾功能和电解质。Ambisome(AmBisome)是一种抗真菌药物,其主要成分是阿莫夫洛星(AmphotericinB)。它主要用于治疗严重的真菌感染,具有以下疗效:1.抗真菌活性,抑制多种真菌的生长和繁殖。2.治疗各种念珠菌感染。3.治疗血液系统真菌感染。该药品在治疗相关疾病方面表现出色,疗效显著、安全性高。

Ambisome (安必素) is a medication commonly used to treat fungal infections. It is an antifungal medication that belongs to the class of drugs known as liposomal amphotericin B. While Ambisome is effective in treating many fungal infections, it is important to be aware of its potential side effects. In this article, we will discuss the possible side effects associated with Ambisome treatment.

1. Overview of Ambisome:

Ambisome, also known as amphotericin B liposomal, is a medication primarily used to treat serious fungal infections. It is often prescribed when other antifungal agents have failed or cannot be used due to their potential side effects. Ambisome works by disrupting the growth of fungi, ultimately killing them and clearing the infection.

2. Common Side Effects of Ambisome:

Like any medication, Ambisome is associated with certain side effects. The most common side effects include:

Fever: Some patients may experience an increase in body temperature while receiving Ambisome treatment. This is usually mild and resolves on its own.

Chills: Chills are another common side effect of Ambisome and are often experienced in conjunction with fever. They may occur immediately after receiving the medication but usually subside over time.

Headache: Headaches are a possible side effect of Ambisome treatment. If headaches become severe or persistent, it is recommended to consult a healthcare professional.

Nausea and vomiting: Ambisome can cause gastrointestinal disturbances such as nausea and vomiting. These symptoms can usually be managed by taking the medication with food or as directed by the healthcare provider.

3. Less Common Side Effects of Ambisome:

In addition to the common side effects mentioned above, a few less common side effects have been reported with Ambisome use. These include:

Anemia: Ambisome may cause a decrease in red blood cell count, leading to anemia. Symptoms of anemia include fatigue, weakness, and shortness of breath.

Kidney problems: In rare cases, Ambisome can cause kidney-related complications, such as kidney damage or impaired kidney function. Regular monitoring of kidney function is often recommended during treatment.

Liver abnormalities: Ambisome may cause liver enzyme abnormalities, which can be detected through blood tests. If liver abnormalities persist or worsen, medical attention is necessary.

4. Allergic Reactions:

While rare, allergic reactions can occur with the use of Ambisome. Signs of an allergic reaction may include rash, itching, swelling, severe dizziness, or difficulty breathing. Any signs of an allergic reaction should be reported to a healthcare professional immediately.

It is important to note that the above list of side effects is not exhaustive, and individual experiences may vary. It is essential to discuss any concerns or potential side effects with a healthcare professional before starting Ambisome treatment.

In conclusion, Ambisome is an effective antifungal medication used to treat various fungal infections. While generally well-tolerated, it can cause side effects such as fever, chills, headache, and gastrointestinal disturbances. Less common side effects include anemia, kidney problems, and liver abnormalities. Allergic reactions are rare but possible. If you experience any concerning symptoms while taking Ambisome, it is crucial to consult your healthcare provider for further assessment and guidance.